Genesis may refer to:

Literature and comics

• Genesis (DC Comics), a 1997 DC Comics crossover
• Genesis (Marvel Comics), a Marvel Comics villain
• Genesis, a fictional character from the Preacher comic-book series
• Genesis, a 1951 story by H. Beam Piper
• Genesis: The Origins of Man and the Universe, a 1982 science text by John Gribbin
• Genesis, a 2000 story by Poul Anderson
• Genesis (novel), a 2006 work by Bernard Beckett
• Genesis, a 2007 story by Paul Chafe
• Genesis (journal), a scientific journal of biology
• Genesis (magazine), a pornographic magazine
• Genesis Publications, a British publishing company
• Genesis, a graphic novel by Nathan Edmondson
• The Book of Genesis (comics), comic-book adaptation illustrated by Robert Crumb

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